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The purpose of this study was to examine the effect of the L-Alanyl-L-Glutamine dipeptide (AG) and electrolyte drink (ED) on cognitive function (NeuroTracker) following endurance exercise, in order to measure the effects of rehydration effectiveness.

12 male endurance athletes performed four trials, each consisting of running on a treadmill at 70% of VO2max for 1h, then at 90% of VO2max until exhaustion. One trial consisted of no hydration, another required ingestion of only a sports electrolyte drink (ED) and two trials required ingestion of a low dose (LD) and high dose of AG (HD) added to the ED. Cognitive function was measured through NeuroTracker baselines pre and post-exercise.

Before rehydration, subjects lost on average 2.4% of their body mass. Pre-post rehydration changes showed HD to be the most effective in aiding cognitive function, and electrolyte only having questionable benefit.

To investigate the extent to which older people's abilities predict biological motion cues to declines with natural aging, and to see if any such effects can be reversed through a NeuroTracker training intervention.

41 older adults with mean age of 68yrs old were divided into trained, active control (placebo), and passive control (no training) groups. They were measured on a standardized BMP post training, which consisted of 15 NeuroTracker sessions distributed over 5 weeks.

Only the NeuroTracker trained group showed transfer to BMP, who demonstrated substantial improvements in processing BMP at 4m. The conclusion was a clear and positive transfer of perceptual-cognitive training onto a socially relevant ability in the elderly.

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Several studies have shown that aerobic exercise can slow age-related cognitive decline, and in some cases, improve cognitive function in the older population. The purpose of this study was to investigate for the first time, the effects of resistance training on cognitive function, as measured by changes in NeuroTracker measures.

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25 older adults with a mean age of 70yrs were split into a trained group (6 weeks of resistance exercises), and an untrained group. Perceptual-cognitive ability was measured pre and post training using NeuroTracker baselines.

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The older adults who performed six weeks of resistance training experienced significant improvements in perceptual-cognitive function as measured by NeuroTracker. Resistance training may therefore be an effective means to slow age related cognitive decline.

To examine if NeuroTracker training transfers to useful field of view (UFOV) performance, a measure strongly associated with driving performance.

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Twenty healthy young adults between the ages of 23 and 33 years were recruited and evenly assigned to either a NeuroTracker training program or active control group using a math game (2048). Both groups completed 5 hours of training distributed over 5 weeks. Both groups completed pre-post standardized assessments of UFOV.

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The NeuroTracker training group exhibited significantly improved UFOV performance, whereas the active control group showed only a small, statistically nonsignificant improvement in the task. The researchers suggest that NeuroTracker and UFOV performance are likely dependent on overlapping cognitive abilities, and that these abilities can be trained and measured in young adults which could lead to improving driving safety.

To compare the learning efficiency 3D-MOT (NeuroTracker) with 2D-MOT, and investigate whether any advantages can be reflected by heart rate variability (HRV).

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26 female U15 soccer players completed the 2D- and 3D-MOT tasks with the order reversed for half of the participants. HRV measures were recorded live during the training.

The female soccer players displayed higher learning efficiency in the 3D-MOT task than in the 2D-MOT. HRV analysis revealed that the training had some stimulation associated with inducing flow states in 2D, but that this effect was significantly greater with 3D-MOT. The researchers concluded that this study highlights the role of flow experience in the utility and applicability of 3D-MOT in soccer sport.

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To examine the influence of nutritional intake on visual perceptual-cognitive performance, measured by NeuroTracker, in young healthy adults.

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98 healthy men (38) and women (60) aged 18–33 years maintained their usual dietary intake while completing NeuroTracker 15 sessions of NeuroTracker over a 15-day period. Food logs and extensive lifestyle measures including body composition, cardiovascular health, sleep and exercise patterns, and general readiness to perform were collected for analysis.

Males consumed significantly more calories, macronutrients, cholesterol, choline, and zinc and performed significantly better on NeuroTracker than the females. Participants who consumed more than 40% of kcals from carbohydrates, less than 24% of kcals from protein, more than 2,000 μg/day lutein/zeaxanthin or more than 1.8 mg/ day of vitamin B2 performed significantly better on NeuroTracker than those who consumed less than those amounts. The researchers concluded that perceptual-cognitive performance is positively influenced by higher carbohydrate, lutein/ zeaxanthin, and vitamin B2 dietary intake, while high protein consumption had negative impacts.

To investigate the feasibility of using a remote therapeutic cognitive intervention for brain injury survivors using an at-home training program.

20 older female and male adults were assessed for cognitive health status using a self-report questionnaire and the Mini-Mental State Examination (MMSE) and deemed cognitively healthy. The at-home participants were provided with NeuroTracker training and completed 20 training sessions over 5 weeks. Participant recruitment, retention, adherence, and experience were used as markers of feasibility. Individual session scores, overall improvement, and learning rates between groups was also assessed.

The remote intervention was found to have strong feasibility overall. This was supported by high recruitment and retention, 90% participant adherence, along with ease of use of the program. Differences in screen size and 3D technology showed no differences on cognitive benefits achieved from training, with significant improvements in task performance across the program, which was also equivalent to lab-based training. The researchers concluded that NeuroTracker provides a promising at-home option for cognitive training for cognitively healthy adults and brain injury survivors.

To investigate if the typically declining perceptual-cognitive abilities of healthy older people can be improved with NeuroTracker training.

20 younger adults (mean age 27 years old) and 20 older adults (mean age 66 years old) completed 3-hours of NeuroTracker training distributed over 3 weeks.

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Although older adults had significantly lower NeuroTracker scores than older adults, they demonstrated a strong learning response to the training, equivalent to their younger peers. By the end of the training program the older adults closely matched the initial baseline performance of younger adults. Although the results demonstrate a decline in perceptual-cognitive functions from healthy aging, the results suggest this decline can be quickly reversed with a short training intervention.

To examine the practical efficacy of cognitive enhancement interventions through a gold-standard template for assessing use of such tools, and to assess NeuroTracker evidence against the template for enhancing attention, working memory and visual information processing speed.

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To assess cognitive tools and NeuroTracker specifically against the following gold-standard criteria and with qEEG findings on changes in neuroelectric brain activity: 1. Robust transfer effects, 2. No Side Effects or Risk of Toxicity, 3. Minimal time and monetary investment, 4) Lasting effects, 5) No ethical issues, 6) Can be used in combination with other interventions, 7) Can be applied to any population.

3-hours of training over 5-weeks with NeuroTracker demonstrated robust effects on attention, working memory, and visual information processing speed as measured by neuropsychological tests. Corresponding changes measured by qEEG were also corroborated these intervention effects. NeuroTracker was concluded to meet the gold standard criteria in points 1, 2, 3, and 5, with some evidence to support the other points, but further research needed.