Science

To investigate if perceptual-cognitive training can provide a proactive intervention to enhance cognition in older adults with memory problems.

47 healthy participants aged 60-90 with subjective memory problems were divided into active and control groups. All participants completed three robust neuropsychological assessments over a three- month period. Active participants completed these before, after and following a 7 week NeuroTracker training intervention.

The NeuroTracker trained group improved significantly on the task, with significant or major transfer to scores in memory tasks (e.g., CVLT-II: Immediate Free Recall; Short-Term Memory Recall, and Long- Term Memory Recall), working memory tasks (e.g., Digit Span Backward) and cognitive flexibility tasks (e.g., D-KEFS Verbal Fluency Category Switching and D-KEFS Verbal Fluency Letter Fluency). NeuroTracker scores also correlated to the scale of these improvements for processing speed, memory performance, and cognitive flexibility. Furthermore, some increased transfer benefits were found one month after the training intervention, potentially indicating heightened neurogenesis and promise for neuroplastic cognitive rehabilitation. The overall results suggest that this form of perceptual-cognitive training can significantly enhance cognition in a sustained way, with a relatively short training intervention.

To investigate if a short NeuroTracker training intervention could improve high-level cognitive abilities in elderly populations.

46 participants, aged 63-87 years old completed pre-and-post neuropsychological assessments for selective attention, psychomotor speed, and cognitive flexibility. Active participants completed 21 NeuroTracker sessions (approx. 2 hours of training) over 7 weeks, between pre-and-posts tests. Controls did no training.

Controls showed no change in pre and post tests. In contrast the active NeuroTracker group experienced significant gains in cognitive flexibility, psychomotor speed, and selective attention, and similar improvements in a combined assessment of psychomotor speed and cognitive flexibility.The researchers concluded that NeuroTracker presents a promising tool for recovering and improving these high-level cognitive abilities in older populations.

To investigate the effectiveness of NeuroTracker training with elite volleyball players as a form of off-court cognitive performance training.

43 elite volleyball athletes performed pre—post NeuroTracker baselines, along with several transfer tests. The active group completed an 8-week NeuroTracker training program in-between pre-post tests, which also included volleyball specific dual-tasks. The control group did no NeuroTracker training, but completed regular volleyball training.

Controls showed no change in pre-post NeuroTracker baselines, while the active group approximately doubled their NeuroTracker speed thresholds. Near transfer tests for sustained attention and processing speed showed significant gains for the NeuroTracker group only. A far transfer motor-skill test was used but was of insufficient difficulty to signficantly differentiate the active and control groups. The researchers concluded that NeuroTracker provides an example of an effective method for improving athlete's cognitive capacities with an off-court training intervention.

To investigate the effects of motor and perceptual dual-task NeuroTracker training over time, and in particular to see if performing prior NeuroTracker consolidation training significantly influences these effects.

‍

71 participants were assigned either just NeuroTracker training (iMOT), NeuroTracker with a decisionmaking task (Combi), NeuroTracker consolidation training then with a decision-making task (Consol), or an isolated decision-making task (iDM). The decision-making task involved a motor-response reaction to a simulated birdie with a real badminton racket. Performance was measured through NeuroTracker speed threshold, decision accuracy, and reaction time.

Firstly the results demonstrated that the dual-task component significantly affects NeuroTracker speed thresholds. Secondly that this effect is reduced with training over time. Thirdly that this effect is reduced further when consolidation training on just NeuroTracker is completed beforehand. Additionally, decision-making speed, reaction time and accuracy improved with dual-task training. Overall this study provides evidence that NeuroTracker consolidation training is an effective method for accelerating learning rates across multiple performance domains.

To investigate if NeuroTracker training can improve perceptual-cognitive skills related to decision-making skills for law enforcement officers.

40 elite law enforcement officers completed a pre-post test experiment on a video based simulated task environment to establish baseline scores for situational awareness, anticipation and decision-making skills. Participants were randomly assigned to training, control and passive groups. The training group completed NeuroTracker sessions around duty schedules over a period of three-weeks. Pre- and post-testing was scored by five police procedures subject-matter-experts.

The simulated task results showed an average decline in scores, the control participants remained unchanged, while the NeuroTracker group showed moderate increases. Improvements in NeuroTracker scores were observed overall, but varied atypically. Although some far transfer effects to law enforcement decision-making abilities were seen, fatigue and stress-related effects of active duty may have influenced results.

This study investigated the effects of a simulated game-situation cognitive load (NeuroTracker) on lower limb biomechanics, using a landing task relevant to straining of the Anterior cruciate ligament (ACL). ACL injuries are known to be one of the most sports common injuries, and occurrence has been linked to cognitive factors.

7 college level healthy athletes (soccer, volleyball, football) performed 16 single-leg landing trials involving a jump forward and a lateral jump to the opposing leg. These movements were measured via force plates and motion capture of the legs and pelvis using 36 markers. The NeuroTracker task was assigned randomly to half of the trials (dual-task procedure), with jumps performed during the tracking phase.

While NeuroTracking hip and/or knee kinematics measurements were significantly different for all participants. The largest change was found with knee abduction angle, known to be most associated to ACL injury. Of the 7 participants, 4 showed biomechanical changes from the added NeuroTracker task that revealed increased ACL strain associated with ACL injury. Based on the preliminary findings, the researchers hypothesize that a NeuroTracker training intervention may reduce risk on of non-contact ACL injury, and will perform a larger study with more detailed biomechanical analysis.

To assess the inhibitory effects of physiological fatigue on cognitive function in elite athletes, and to determine if perceptual-cognitive conditioning can reduce any such effects.

22 rugby players from the Top 14 French Professional Rugby League were divided into two groups. The trained group underwent 15 NeuroTracker Core training sessions, and the untrained group did only 3 Core sessions (sitting) to determine an initial baseline measure. All the athletes were then assessed on NeuroTracker while performing on an exercise bike at 80% of their maximum heartrate.

For the trained group, NeuroTracker speed thresholds remained within 0.03% of the range of their baseline (performed sitting). For the untrained group, NeuroTracker speed thresholds dropped by 30% from their predicted baseline. Firstly, the findings suggest that physical fatigue can significantly reduce high-level cognitive functions elicited by the NeuroTracker task, even with seasoned professionals. Secondly, the results also indicate that such effects can be mitigated with prior perceptual-cognitive conditioning, with as little as 90 minutes of distributed training.

To test the theory that driving performance is strongly associated with dynamic processing of multiple objects, by evaluating if NeuroTracker measures correlate with older driving performance in simulated scenarios.

30 experienced drivers with ages ranging from 65-85 years old were tested on one session of NeuroTracker (3D-MOT), and completed up to 3 driving scenarios on the STISIM 3.0 driving simulator. 5 unexpected events were included in the scenarios to test crash risk. The correlations between NeuroTracker speed thresholds and simulator measures (crash rate, lane deviation) were then calculated.

Highly significant correlations were found between NeuroTracker thresholds and both crash rate and lane deviation in the highway driving scenarios. Lower NeuroTracker scores were strongly associated with lane deviation during highway merging, and higher NeuroTracker scores related to participants being less likely to crash across different scenarios, and to have better overall lane maintenance skills. This study adds plausibility to the idea that a multiple object tracking test such as NeuroTracker could be a candidate for inclusion in an assessment battery for older drivers.

To evaluate the potential for sports vision training to improve objective and subjective visuomotor function in a low vision patient.

A 37-year-old woman with Usher syndrome underwent a 14-week sports vision training program with pre-post cognitive assessments.

The patient was able to improve the use of remaining visual abilities. A 27 to 31% improvement in hand-eye coordination was achieved along with a 41% improvement NeuroTracker performance. The patient also subjectively reported clear improvements in visual abilities. The researcher concluded sports vision training may reduce the impact of the reduced visual function and aid in activities of daily living.

To investigate how multiple object tracking abilities (NeuroTracker) may enhance strategies for maintaining spatial awareness and optimal player performance in soccer. Additionally, to examine the relationship between aerobic capacity and multiple object tracking capacity.

7 competitive female soccer players completed a 90-minute intermittent soccer performance test (iSPT) on a Curve™ non-motorized treadmill (cNMT) with monitoring of VO2max. This involved six individualized running, jogging or walking speeds, and a half-time period, to simulate demands in soccer competition. NeuroTracker baselines were completed three times during each half of the iSPT.

The fatigue associated with 90 minutes of soccer specific running negatively influenced running performance during the second half. However, increased aerobic capacity appears to be associated with an attenuation of cognitive decline during 90-minutes of soccer specific running. Results of this study indicate the importance of aerobic capacity on maintaining spatial awareness during a match.

The objective of the study was to examine MOT capability at different levels of cognitive load (tracking 1,2,3, or 4 objects) and its association to higher level processes, particularly fluid reasoning intelligence.

‍

70 adult participants (mean= 23 years of age) completed NeuroTracker and were then assessed on the Weschler Abbreviated Scale of Intelligence 2 test. Participants were asked to track one, two, three and four targets out of a total of 8 spheres for eight seconds.

The results showed that as the number of targets increased, the average speed the participants successfully tracked all the objects decreased. This finding allowed the researchers to confirm that average speed score can be used as a suitable metric for MOT and in turn, attention resource capacity. As a result, the outcomes indicate that visual tracking capability is positively associated with fluid reasoning intelligence. Consequently, this finding demonstrates that there is a link between fluid reasoning intelligence and MOT capability, especially in conditions of high load (tracking 4 out of 8 targets).

To investigate if an unsupervised remote NeuroTracker training intervention could subjectively improve performance outcomes with elite athletes across a range of different sports.

‍

54 elite athletes from boxing, wrestling, women’s handball, women’s soccer, orienteering, biathlon, alpine skiing, sled hockey, badminton and table tennis completed at least four NeuroTracker sessions per week over a 5 week period. The athletes trained independently from the researchers, using personal NeuroTracker accounts. They were also not given any instructions on the training, to avoid potential biases. All the athletes completed pre and post Athlete Satisfaction Questionnaires (7 point Likert scale), to self-assess their current performance status.

‍

‍

Almost all the participants completed at least the minimum of 4 NeuroTracker sessions per week, indicating a high compliance. On average the athletes experienced an improvement in normalized NeuroTracker speed thresholds of 39% by the end of the 5 weeks. The results of Athlete Satisfaction Questionnaires showed an improvement from a rating of 18.9, to 19.2.

To investigate the cognitive characteristics of individuals with with Autism compared to neurotypical individuals in response to different NeuroTracker loads and feedback.

27 adolescents and adults with Autism and 28 neurotypical adolescents and adults ASD were tasked with performing NeuroTracker at low load (1-target tracking) and high load (4-target tracking) across two sessions of training. Half of the participants received feedback on each trial, and half did not.

‍

Although participants with Autism scored lower than neurotypicals, high load sessions were tolerated equally in comparison to low load sessions. Feedback improved NeuroTracker performance overall, except for participants with Autism on the high load sessions. Participants with Autism receiving feedback scored better than neurotypical participants without feedback, but only on the low load sessions. The results suggest that individuals with Autism can perform NeuroTracker at different loads, and that feedback aids performance at low difficulty levels.

To combine several tests known to assess driving fitness and propose a methodology to bring these together under a single index termed the ‘Driver’s Safety Index’.

‍

115 licensed drivers between the ages of 18 and 86 were separated into two groups: 64 young participants (average age of 29 years), and 51 older participants (average age of 77 years). Each participant was assessed on three different experimental phases. 1. Visual tests: visual acuity test (V1), stereoscopic vision test (V2), and a binocular visual field test (V3). 2. Simulator driving tests across 3 difficulty based scenarios: highway (low), rural (medium) and city (high). 3. NeuroTracker as a visuo-cognitive test. A wide range of driving performance metrics from the simulator test were analyzed for correlations with the visual tests, age, and NeuroTracker scores.

‍

There were limited correlations between driving performance and the visual tests. High NeuroTracker scores correlated strongly with high driving performance, and low scores with low driving performance, along with a strong relationship for crash risk. NeuroTracker scores were also a better predictor of driving performance than age. Driving abilities are strongly associated with NeuroTracker scores. These findings highlight the importance of visuo-cognitive abilities in the assessment of driving abilities. This study paves the way toward a single, common indicator of driving behaviour. The study authors recommend that NeuroTracker should be a component in the battery of tests for obtaining or renewing a driving license.

To investigate if NeuroTracker baselines can be used to differentiate athletic experience and class of sport.

101 female (36) and male (67) athletes at Universidad Playa Ancha (Spain) in soccer, basketball, volleyball, rugby, handball, swimming, athletics, table tennis and rowing, completed NeuroTracker baselines. These were all completed at noon, following intense workouts the day before. The sports were classified into open structure (e.g. soccer) and closed structure (e.g. swimming) groups, due to expected differences their cognitive demands.

Overall, statistical analysis showed that NeuroTracker baselines correlated significantly with sex, amount of athletic training, and class of sport. The researchers conclude that these results show that NeuroTracker provides an accessible measure of perceptual-cognitive function that relates significantly to athletic performance variables in university athletes.

To to determine whether a hydration plan based off of an athlete’s sweat rate and sodium loss, improves anaerobic and neurocognitive performance during a moderate to hard training session, as well as heart rate recovery from the session.

‍

15 NCAA collegiate athletes from Merrimack College from multiple sports first underwent a qualitative assessment for hydration habits and knowledge, then were assessed for sweat loss, and randomly assigned to either a prescription hydration plan (PHP) or asked to continue with their normal hydration habits (NHP). All participants completed underwent performance assessments prior, during, and immediately after a moderate to hard sports-specific training session. Assessments included NeuroTracker baselines, standing long jump, heart rate and Vo2 Max monitoring, as well as sodium and sweat loss monitoring.

‍

NeuroTracker baselines provided a clear indication that a prescription hydration plan has a significantly better influence on perceptual-cognitive functions, both pre and post physical training, compared to a normal hydration plan. Overall, the researchers conclude that this is the first investigation to show that an individually tailored hydration plan improves athletic performance for collegiate athletes engaged in a variety of sports.

Working Memory (WM) capacity has been linked to performance on a wide range of elementary and higher order cognitive tasks. Due to evidence suggesting that NeuroTracker speed thresholds are an indicator of the quality of high-level brain function, and because it is an adaptive task, the researchers selected NeuroTracker to investigate whether training could improve WM capacities. A further reason was to test a training approach with short intervention times for practical military implementations for the Canadian Armed Forces.

41 soldiers in the Canadian Armed Forces volunteered for the study. First they were tested on three WM span tasks: word (verbal) span, matrix span, and visual span, establishing a baseline measure for each test. Participants were then distributed evenly into 3 groups based on demographic and cognitive factors,Experimental group: performed 10 NeuroTracker Core sessions over a 2 week periodActive control group: performed an adaptive dual n-back task over a 2 week period Passive control group: No activity over a 2 week periodAt the end of the two weeks, the three WM span tests were retaken.

For the NeuroTracker group, speeds thresholds increased considerably over the 10 sessions, and training resulted in a significant pre-post increase in word span, matrix span, and visual span, with medium to large effect sizes. In contrast, for the active control, group training did not alter any of the WM span measures. Similarly, WM span measures did not alter for the passive control group. The researchers concluded that a short amount of NeuroTracker training can benefit WM capacity in a military sample. Additionally, the consistent NeuroTracker improvements across each type of WM span reflect a primarily domain-general construct (a generality of WM capacity).

‍

The goal of this multi-year research project was to develop methods for assessing the efficacy of training (including live and simulated platforms) by validating measures of cognitive workload that characterize skill acquisition.

‍

10 evaluation pilots (100-300 flight hours of experience) were selected to perform low, medium and high difficulty flight manoeuvres in both a jet flight simulator and live jet flight (Aero Vodochody L-29 jet trainer) using experimental conditions. During flight ECG data (NeXus-4) and eye-tracking data (Dikablis) was collected. Flight performance was analysed for altitude, roll, and vertical speed errors, and cognitive workload was subjectively assessed (10-point Bedford Workload Scale). As a validated tool for evaluating perceptual-cognitive skills, NeuroTracker was selected as to measure spare cognitive capacity via extraneous load (Cognitive Load Theory). All pilots first completed home-based NeuroTracker consolidation training (15 Core sessions). NeuroTracker was integrated into the flight testbed. Low, medium and high difficulty flight manoeuvre tests were performed by all pilots, both without NeuroTracker, and while simultaneously performing NeuroTracker Core sessions.

‍

Compared to performing NeuroTracker alone, live and simulated flight across all manoeuvres, caused a drastic decrease in NeuroTracker speed thresholds (average of ~97%). This, perhaps for the first time, objectively demonstrated that jet flight involves very high intrinsic cognitive loads. Live flight resulted in lower NeuroTracker speed thresholds and physiological performance than simulated flight, with greater differences for higher difficulty maneuverers. This evidence suggests that physiological and cognitive loads are significantly heavier in live flight, supporting the theory that that brain dynamics differ in real-world environments compared to those of a laboratory.